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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
31.52
Human Site:
S517
Identified Species:
46.22
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S517
I
K
K
K
K
H
F
S
E
T
E
A
S
Y
I
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S609
I
K
K
K
K
H
F
S
E
T
E
A
S
Y
I
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S769
I
K
R
K
K
H
F
S
E
T
E
A
S
Y
I
Dog
Lupus familis
XP_547953
806
90703
S524
I
K
K
K
K
H
F
S
E
T
E
A
S
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S502
I
R
K
K
R
L
F
S
E
S
E
A
S
Q
I
Rat
Rattus norvegicus
Q63531
735
82865
S457
D
K
S
K
R
D
P
S
E
E
I
E
I
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
E435
Q
K
K
K
H
F
S
E
T
E
A
S
S
I
M
Chicken
Gallus gallus
Q5F3L1
789
89022
S507
I
Q
K
K
Q
H
F
S
E
T
E
A
S
H
I
Frog
Xenopus laevis
P10665
733
82620
G465
I
E
I
L
R
R
Y
G
Q
H
P
N
I
I
A
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
I475
Y
G
Q
H
P
N
I
I
T
L
K
D
V
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
D712
L
T
A
S
I
R
M
D
E
D
S
C
R
E
I
Honey Bee
Apis mellifera
XP_395099
910
102507
S537
L
R
R
P
R
P
F
S
D
Q
Q
A
S
R
I
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
T473
I
R
K
L
E
R
F
T
E
S
E
A
A
D
I
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
D474
I
R
K
K
K
H
F
D
E
L
E
A
S
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Y214
F
Q
T
K
Y
R
L
Y
L
V
L
D
F
I
N
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
V420
S
P
E
K
L
Y
L
V
L
A
F
I
N
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
93.3
100
N.A.
66.6
26.6
N.A.
26.6
80
6.6
6.6
N.A.
13.3
33.3
46.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
40
N.A.
40
100
33.3
26.6
N.A.
20
73.3
80
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
7
7
57
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
7
0
0
0
0
7
0
13
7
7
0
13
0
7
7
% D
% Glu:
0
7
7
0
7
0
0
7
63
13
50
7
0
7
0
% E
% Phe:
7
0
0
0
0
7
57
0
0
0
7
0
7
0
0
% F
% Gly:
0
7
0
0
0
0
0
7
0
0
0
0
0
7
7
% G
% His:
0
0
0
7
7
38
0
0
0
7
0
0
0
7
0
% H
% Ile:
57
0
7
0
7
0
7
7
0
0
7
7
13
19
63
% I
% Lys:
0
38
50
69
32
0
0
0
0
0
7
0
0
0
0
% K
% Leu:
13
0
0
13
7
7
13
0
13
13
7
0
0
7
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
7
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
7
7
0
7
% N
% Pro:
0
7
0
7
7
7
7
0
0
0
7
0
0
0
0
% P
% Gln:
7
13
7
0
7
0
0
0
7
7
7
0
0
7
0
% Q
% Arg:
0
25
13
0
25
25
0
0
0
0
0
0
7
7
0
% R
% Ser:
7
0
7
7
0
0
7
50
0
13
7
7
57
0
0
% S
% Thr:
0
7
7
0
0
0
0
7
13
32
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
7
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
7
7
7
7
0
0
0
0
0
32
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _